The dentist who gives Botox every day
Chief Director of Jaejooh Dental Clinic
I am Sohyunsoo, a specialist in Integrated Dentistry.
I have steadily studied botulinum toxin through various academic organizations, including
the Jaw and Facial Aesthetic Reconstruction Course hosted by the Korean Association of Oral and Maxillofacial Plastic and Reconstructive Surgeons and
the Korean Association of Oral and Maxillofacial Surgeons,
the Botulinum Toxin Course of the Seoul Dental Association,
and the Korean Headache Society, where neurologist MDs are mainly active.
In actual practice as well, among dental clinics, we purchase Xeomin in quantities that even the pharmaceutical company finds surprising.
If you look at the reviews on our Jaejogchi Naver Map page, there are really a lot of Botox reviews.. more than dental treatment reviews.. (ㅎㅎ;;)
I guess we give it too often ㅠㅠ

Director Sohyunsoo’s Instagram story. How much is all of this ㅠㅠ
Xeomin, a pure toxin with no resistance
300,000 KRW for 100 units
Before injecting patients who come in for bruxism Botox,
I explain Xeomin thoroughly.
By now, most people seem to have already researched it and come in knowing the basics,
but I still can’t skip the explanation,
so I give it in detail every time,
and I think that is seen in a positive light.
Shall I share that explanation as it is?
"Among Botox products, we use 'Xeomin.'
You may already have looked into it, but
it is known for having no resistance so far,
which is why it is very popular these days in dermatology.
However, I think the fact that it has no resistance is actually
even more important in dentistry.
That is because we use Botox for therapeutic purposes,
not for aesthetic purposes,
and the amount injected into a single muscle is often more than 20 times greater than the amount used for cosmetic purposes in dermatology,
and because we tell patients to receive it regularly, once every six months,
the conditions are much less favorable for 'resistance development,'
so we use only Xeomin, which has been known from the start as a product with no resistance."
People who have received Xeomin from us would probably think it was a recordingㅋㅋ because it is exactly the same as what they heard at the clinic...
Since I also give Botox so often,
those same words now come out automatically.
It is a German botulinum toxin made by MERZ Aesthetics, the pharmaceutical company famous for Ulthera, the ultimate lifting procedure.
Comparison with domestic Coretox
200,000 KRW for 100 units
Sometimes I see places incorrectly advertising Xeomin as the world’s only pure toxin.
In fact, there are currently three types of pure toxin worldwide:
{Xeomin, Coretox, Daxxify}
and among them, Daxxify
has not yet been released in Korea.
Among domestic products, there is a product called Coretox,
which is known to have 'less' resistance.
Because Coretox is a bit cheaper,
it is often compared with Xeomin.
So, cautiously speaking,
I personally think Xeomin is better than Coretox,
but Coretox is also a sufficiently good product,
and that is my view.

Cover of a toxin-related journal
In February 2024, in a journal called TOXINS
Isn’t that a journal with a solid foundation, even from the name alone?
In it was published a paper titled
'Complexing Protein-Free Botulinum Neurotoxin A Formulations: Implications of Excipients for Immunogenicity'
and the gist of it was ultimately that
'Xeomin is indeed made only of substances without resistance,
whereas Coretox is not.'
Of course, the characteristic of having 'less' resistance is also a very excellent trait.
Korean pharmaceutical companies are truly impressive.
Because there is no complex protein, which is the main cause of resistance,
clinically speaking, there is practically no difference.
Domestic toxins have gone through many twists and turns in Korea, and because of various concerns, in the past at dental clinics we used to explain to patients,
"I’d like to stock it because it’s cheaper,
but for now, I’m only using Xeomin."
However, now I think Coretox is also a sufficiently good product,
so we use both.
So,
for Xeomin, I explain it as "known so far to have 'no' resistance..."
and for Coretox, I begin with "known to have 'less' resistance..."
There is a reason for the wording.
Every word choice has its details.
Even Xeomin has, according to the papers, 'so far'
been shown to have no resistance,
which is why I deliberately add the word 'so far'...
I’m really not someone who runs a dental clinic carelessly.
The original BOTOX, Allergan
200,000 KRW for 50 units
The one that first developed botulinum toxin
and made the product name 'Botox' used almost like a common noun
'Allergan' Botox!
It is the oldest original botulinum toxin.
This product is not a 'pure toxin,'
so it does contain byproduct proteins that can cause resistance,
but it is an excellent product with outstanding purification technology
and very stable drug quality control.
In particular, because it was the first botulinum toxin formulation to receive FDA approval in the United States for migraine treatment,
we also carry Allergan Botox.
What I just mentioned about 'quality control' is actually, in a way, a very important feature of how the drug works.
If a product says it contains 100 units of botulinum toxin,
can you really be confident that it actually contains 100 units?
That is the issue.
All products inevitably have some margin of error,
but how narrowly can that be controlled?
Especially in 'drugs,' how important is that characteristic?
I handle
Xeomin and Allergan Botox,
and at least for those two products, I think they are trustworthy...
That’s why.
What about domestic products?
I can’t know every product,
but in that regard, among domestic products,
Daewoong Pharmaceutical’s 'Nabota' (FDA-approved) and
Hugel’s 'Botulax' are known to be stable.
There are probably many other stable products too.
Once again, Korean pharmaceutical companies are truly remarkable.
I really do think about all sorts of things, don’t I?

Photo taken in the drug storage room of Jaejogchi Dental Clinic
Bruxism Botox is a matter of
fine differences in dentistry
First of all, by default,
in addition to the 'masseter' toxin commonly known as square-jaw Botox,
we make it a rule to perform it together with the 'temporalis' muscle as well.
And because the masseter muscle also consists of
a deep layer and a superficial layer,
this must be taken into account when injecting the toxin.
That way, after the injection, every time you chew something,
you can prevent the side effect of the masseter popping out like a hard candy.
By properly adjusting the amount of saline mixed in,
we can prevent the medication from spreading too much to other muscles,
so to speak, fine details can differ a little in order to minimize side effects such as hollow cheeks.
Because I understand all the concerns you may have,
you can come in with peace of mind :-)

2019 Seoul Dental Association Botox Training Certificate
Looking at this certificate, I can feel again the tension from the first time I injected toxin into a person (a senior director) at the 2019 training course ㅋㅋ
I had no idea I would end up giving BOTOX this often...
I was such a fresh beginner dentist
Now it’s already been 7 years, counting by year, since I started doing head and neck toxin injections?
Time really flies...
For fellow directors reading this, didn’t I really prepare hard for opening a dental clinic?
Anyway, even in running a clinic,
I won’t make decisions like,
'Everyone else uses this a lot, so~'
'People say this is good, so~'
'People say this is trendy these days, so~'
'I’ll just do that too~'
Instead, I will be a <skilled dentist> who carefully examines and analyzes each thing one by one,
asking why something is good if it is good,
whether there really is no alternative,
and whether what is known is truly fact.
I will always strive to do my best.
Thank you.