Female Pattern Hair Loss: A New Path in Treatment (Bicalutamide — a Drug Used to Treat Prostate Cancer)

Hair loss is a problem that causes psychological stress for many people.

In particular, female pattern hair loss can significantly reduce confidence in one’s appearance,

so finding an effective treatment is very important.

Recent research has found that a treatment combining bicalutamide and minoxidil may produce better results than minoxidil alone.

Source: Libório RdS, Motta AVd, Miot HA, Müller Ramos P, Bicalutamide 25 mg associated with minoxidil 1 mg versus minoxidil 1 mg for female-pattern hair loss: A randomized doubleblind clinical trial, JAAD International (2025), doi: https://doi.org/10.1016/j.jdin.2024.12.002

Bicalutamide

Bicalutamide is a drug originally used to treat prostate cancer, and it has the effect of inhibiting the action of male hormones.

Because of this property, it is drawing attention for its potential to help address hormonal issues in hair loss treatment as well.

Key Points of the Study

1. Need for the Study

Female pattern hair loss occurs due to various causes, such as hormonal changes, genetic factors, and stress.

The existing treatment minoxidil has the effect of promoting hair growth, but in many cases it does not provide satisfactory results for all patients.

To overcome these limitations, the research team tried combining minoxidil (1 mg) and bicalutamide (25 mg).

2. Study Method

• Study design: The research team randomly divided participants into two groups, with one group using a combination of minoxidil and bicalutamide and the other using minoxidil alone.

• Participants: Patients diagnosed with female pattern hair loss took part in the study.

• Evaluation items: Hair growth rate and the effect of suppressing hair loss progression were compared between the two groups.

3. Study Results

The group using bicalutamide and minoxidil together showed better results in the following areas.

• Hair density increased significantly.

• Progression of hair loss was greatly suppressed.

• Side effects were mild, and the safety of the drug was confirmed.

Source: Libório RdS, Motta AVd, Miot HA, Müller Ramos P, Bicalutamide 25 mg associated with minoxidil 1 mg versus minoxidil 1 mg for female-pattern hair loss: A randomized doubleblind clinical trial, JAAD International (2025), doi: https://doi.org/10.1016/j.jdin.2024.12.002

This study presents a new option for patients with female pattern hair loss who have not achieved sufficient results with existing treatments.

In particular, bicalutamide is being evaluated as a drug that may directly address hormonal issues, one of the root causes of hair loss.

These research findings could bring major changes to the treatment of female pattern hair loss.

• Advantages: Combination therapy shows the potential to maximize hair growth effects.

• Caution: Additional clinical studies are still needed to determine whether it is suitable for everyone.

Female pattern hair loss: finding hope through a new treatment

Conclusion

Female pattern hair loss is not simply a matter of appearance; it also has a major impact on quality of life and confidence.

The combination therapy of bicalutamide and minoxidil presented in this study is drawing attention as an effective

treatment alternative, and it is expected to offer hope to many patients.

If more clinical studies are conducted in the future, this method is highly likely to become a new standard for treating female pattern hair loss.

It is time for hairhair, Kim Jino was here.

Pilsaeng Sinmo (必生新毛).

Related paper

Libório RdS, Motta AVd, Miot HA, Müller Ramos P, Bicalutamide 25 mg associated with minoxidil 1 mg versus minoxidil 1 mg for female-pattern hair loss: A randomized doubleblind clinical trial, JAAD International (2025), doi: https://doi.org/10.1016/j.jdin.2024.12.002

[This post is written directly by the director to provide information in accordance with Article 56, Paragraph 1 of the Medical Service Act. Hair transplant surgery and treatment may have side effects, and you should make a careful decision after consulting with a specialist.]