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Hair Loss Treatment Using Adenosine

New Hair Institute · 김진오의 뉴헤어 프로젝트 · February 18, 2025

Hair loss is a condition that places a psychological and social burden on many people. In particular, androgenetic alopecia, which can occur in both men and women, is strongly infl...

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This page is an English translation of a Korean Naver Blog archive entry. For exact wording and source context, verify against the Korean archive original and the original Naver post.

Clinic: New Hair Institute

Original post date: February 18, 2025

Translated at: April 29, 2026 at 2:36 PM

Medical note: This translation does not guarantee medical accuracy or suitability for treatment decisions.

Hair loss is a condition that places a psychological and social burden on many people.

In particular, androgenetic alopecia, which can occur in both men and women, is strongly influenced by genetic factors, and to date, minoxidil, finasteride, and dutasteride have been the main treatments used.

However, recent research has shown that adenosine (Adenosine) is emerging as a new substance that is effective for hair loss treatment.

Hair Loss Treatment Using Adenosine image 1

Adenosine is a nucleoside that is responsible for various physiological functions in the body, and it plays an especially important role in vasodilation and promoting cell growth.

This study found that adenosine may help prevent hair loss by suppressing androgen receptor signaling.

  1. Analysis of changes in gene expression
  • The researchers examined changes in gene expression in scalp dermal papilla cells to compare the differences between minoxidil and adenosine.

  • As a result, adenosine was shown to inhibit androgen receptor activity and activate signaling pathways related to hair growth.

  1. Hair follicle culture experiment
  • When human hair follicles were cultured and the effects of adenosine were tested, the growth phase of the hair follicles was confirmed to be extended.

  • This means that adenosine has a positive effect on the growth and maintenance of hair follicles.

  1. Clinical trial results
  • The researchers compared two groups that used 5% minoxidil and an adenosine combination formula (APN, 0.75% adenosine, 1% panthenol, 2% niacinamide) for 4 months.

  • As a result, hair density increased significantly in both groups,

and the adenosine combination formula (APN) group also showed effects at a level similar to minoxidil.

Hair Loss Treatment Using Adenosine image 2

This study shows that adenosine has significant potential as a treatment for hair loss.

In particular, it is noteworthy that it has fewer side effects than existing treatments and works by directly inhibiting androgen receptors, showing a mechanism that differs from minoxidil.

However, there is still a lack of long-term research, and it has the limitation that it has not yet been sufficiently clinically verified to the same extent as minoxidil or finasteride.

With additional research in the future, it will become clearer whether adenosine can become a new alternative for hair loss treatment.

Hair Loss Treatment Using Adenosine image 3

Hair Loss Treatment Using Adenosine image 4

Hair Loss Treatment Using Adenosine image 5

Hair Loss Treatment Using Adenosine image 6

Hair Loss Treatment Using Adenosine image 7

Adenosine is a substance that is highly likely to bring about a new turning point in hair loss treatment.

It is drawing more attention because, while having a mechanism of action different from existing treatments, it may still induce effective hair growth.

If research progresses further in the future, we will have a wider variety of hair loss treatment options.

I hope this study can become a new source of hope for many people struggling with hair loss!

It is time for hairhair, Kim Jin-oh.

필생신모(必生新毛).

[This post is written directly by the director to provide information in accordance with Article 56, Paragraph 1 of the Medical Services Act. Hair loss surgery and treatment may have side effects, and you should make a careful decision through consultation with a specialist.] ​

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