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Pain Comparison of Rejuran Healer, Rejuran I, and Rejuran HB

Relieve Clinic · 무통 박원장이 직접쓰는 블로그 · August 26, 2025

Hello, I’m Dr. Park from Relieve, where we pursue pain-free treatments. Many people are interested in Rejuran Healer, but they also ask the same question: "Isn’t Rejuran a very pai...

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This page is an English translation of a Korean Naver Blog archive entry. For exact wording and source context, verify against the Korean archive original and the original Naver post.

Clinic: Relieve Clinic

Original post date: August 26, 2025

Translated at: April 20, 2026 at 2:59 PM

Medical note: This translation does not guarantee medical accuracy or suitability for treatment decisions.

Hello, I’m Dr. Park from Relieve, where we pursue pain-free treatments.

Many people are interested in Rejuran Healer, but they also ask the same question:

"Isn’t Rejuran a very painful procedure?"

Then I always answer, "Yes, that’s right. But our Rejuran is a little different."

Pain Comparison of Rejuran Healer, Rejuran I, and Rejuran HB image 1

To get to the point first, the pain from Rejuran can definitely be reduced. And how we control pain is an important factor in determining how consistently a patient can continue treatment.

Today, I’ll explain the pain associated with Rejuran.

Pain Comparison of Rejuran Healer, Rejuran I, and Rejuran HB image 2

Why is Rejuran said to be painful?

Rejuran directly injects PN, a highly viscous substance, into the dermis layer of the skin. PN, a DNA fragment extracted from salmon testes, is more viscous than typical hyaluronic acid and creates a tearing sensation when it enters the skin. So-called patients often say it feels like "being torn off with nail clippers." I was also very surprised when I first received Rejuran myself..

Many doctors say that Rejuran’s pain comes from the dermis being torn, but then why doesn’t it hurt when filler is placed in the dermis? That statement is half right and half wrong.

Pain Comparison of Rejuran Healer, Rejuran I, and Rejuran HB image 3

Pain Comparison of Rejuran Healer, Rejuran I, and Rejuran HB

Rejuran Healer: Standard Rejuran Healer tends to be quite painful. I usually do not use Rejuran Healer alone; instead, I combine ingredients such as skin booster injections or skin Botox in my own way to control the pain. In that case, the pain intensity can be similar to Rejuran HB or even reduced further. In my experience, it felt about 20–30% less painful. (This varies from person to person.)

Rejuran I: This one can be received very comfortably with cream anesthesia alone, as long as the numbing cream is applied well. Just ask for the cream anesthesia to be left on longer..

Rejuran HB+: Because of the pain, many people choose HB instead of Rejuran Healer. Rejuran HB contains only half as much Rejuran ingredient as Healer. So the rumor that its effect is somewhat lower may be true. Of course, there are people who say Rejuran HB alone still works very well. The pain is about half that of Rejuran Healer.

Pain Comparison of Rejuran Healer, Rejuran I, and Rejuran HB image 4

How can we reduce the pain?

I approach all procedures by increasing effectiveness and reducing pain. To do this, in fact, every factor has to be carefully adjusted. Many factors affect pain, such as the ingredients in the numbing cream, how long the cream is applied, the dilution ratio, acidity, temperature, and needle thickness. Through countless experiments, I am searching for the point that minimizes pain as much as possible.

Pain Comparison of Rejuran Healer, Rejuran I, and Rejuran HB image 5

I will keep doing my best until the day when the pain of every procedure is reduced.

This was Dr. Park.

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