Want the Benefits of Rejuran in Apgujeong, but Not the Pain?

Hello.

I am Ryu Hyo-seop, a dermatologist with 22 years of experience.

When I meet patients in the clinic, it is true that they have hopes for skin regeneration and improved elasticity, but they also have fears about the procedure itself. One of the questions I hear most often is this.

“Rejuran is supposed to hurt a lot. Is it really okay to get it?”

“I want the benefits, but is there a way to reduce the pain or a procedure that works well together with it?”

These may seem like different concerns, but in the end, the core issue is one: wanting to get “a comfortable process and clear results.” Today, as an answer to that concern, I will explain everything from the principle of Rejuran to why Rejuran Tox, a special solution unique to Wells Dermatology, can be an alternative for pain.

Table of Contents

1. The principle of Rejuran and the cause of its uncomfortable pain

2. Why Rejuran Tox achieves both pain relief and effectiveness

3. Pre-procedure checklist: 3 questions to reduce pain and embossing

4. Closing remarks

The principle of Rejuran and the cause of its uncomfortable pain

Rejuran, known as the “strongest skin booster,” uses PN (polynucleotide), DNA fragments extracted from salmon, as its main ingredient to fundamentally improve the environment inside damaged skin. It thickens the thinned dermal layer and balances oil and moisture, strengthening the skin barrier.

Although it is an appealing ingredient, why does it cause such intense irritation when injected? Academically, there are two main reasons.

The first is due to the ingredient’s “physical properties.”

PN has a very large molecular weight and a sticky viscosity. The dermal layer of our skin is made up of very dense tissue, and when a highly dense fluid squeezes into the narrow gaps between those tissues, it strongly pushes against the surrounding tissue. The physical pressure generated at this time stimulates nerve endings, causing a heavy, dull, aching sensation.

Second is the “difference in acidity (pH)” from the body’s fluids.

The fluids in our body are mildly alkaline at around pH 7.4, but the original ingredient has a lower, acidic pH. This numerical gap stimulates receptors inside the skin and creates the characteristic “stinging and burning” reaction.

Why Rejuran Tox achieves both pain relief and effectiveness

One of the best combinations I recommend to solve these difficulties for patients is “Rejuran Tox.” Rejuran and skin Botox are both procedures that inject medication into the dermal layer. So if Rejuran and Botox are mixed in advance and injected before the procedure, both effects can be achieved at once.

① Easier dispersion of the medication and pressure relief

Compared with injecting the pure ingredient alone, going through an appropriate mixing process slightly adjusts the viscosity of the medication. This reduces the physical resistance applied to the tissue during injection, significantly lowering the pressure patients feel. In other words, it helps the medication spread more smoothly within the skin.

② Synergistic effect: immediate improvement in pores and fine lines

While Rejuran is responsible for fundamental regeneration of the dermal layer, the mixed toxin ingredient acts on the skin’s superficial micro-muscles and sebaceous glands. Through this, the effect of tightening enlarged pores and smoothing fine lines appears gradually from shortly after the procedure. Patients can experience immediate improvement in skin texture while waiting for the regenerative effect to appear, which leads to very high satisfaction.

③ Control of inflammatory response and swelling

The toxin ingredient can also help reduce the mild redness or swelling that may occur after the procedure. Therefore, Rejuran Tox becomes an even better alternative for those worried about post-procedure bumps or redness.

Pre-procedure checklist: 3 questions to reduce pain and embossing

Has the practitioner accumulated more than 20 years of clinical experience?

The thickness of the skin layer differs from person to person. The injection depth must be precisely adjusted for thin areas such as around the eyes and thicker areas such as the cheeks. If it is too shallow, the pain becomes stronger; if it is too deep, the effect is reduced. Twenty-two years of experience is proven in the manual skill of adjusting this slight difference in depth.

Is there a customized anesthesia system that considers each individual’s pain sensitivity?

It is not enough to simply apply anesthetic cream and wait. You should check whether the clinic identifies the patient’s fear and sensitivity and maintains the appropriate anesthesia time. Wells Dermatology places the patient’s comfort as the top priority in care by considering these aspects.

Are authentic product verification and post-procedure soothing care systematic?

Right after the procedure, the skin is in a very sensitive state. It is essential to check whether there is a professional soothing program that helps embossing subside quickly and, above all, whether the clinic transparently discloses genuine product packaging before the procedure.

Closing remarks

There should never be only painful memories left in the process of becoming prettier. If you know the amazing changes Rejuran can bring but have hesitated because of the barrier of pain, you can now let go of that worry a little.

Rejuran Tox performed at our clinic is a procedure designed not only to maximize results but also to make the process comfortable. The embossing that appears after the procedure is a positive sign that the skin is becoming healthier, and it usually disappears naturally within 1 to 2 days, so you can rest assured.

Skin concerns are different for everyone, but the answer ultimately begins with precise diagnosis and warm care. I will do my best, with 22 years of experience, to help your skin regain its natural radiance.

This was Dr. Ryu Hyo-seop of Wells Dermatology.

Thank you.

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Are you only getting Rejuran? A “perfect combination” that doubles the effects of Rejuran (Rejuran Tox)

Rejuran can improve wrinkles when combined with this? 【Effective Rejuran procedure】