Rejuran vs. Rituo: Which Should You Choose If Your Skin Has Become Thin and Dull?

Hello.

I am Won-shin Lee, a board-certified dermatologist with 23 years of experience.

When I consult with patients about skin boosters, many share concerns like these.

“My skin feels like it has become too thin.”

“My skin feels dry from within, even when I wear makeup.”

“I hear Rejuran is good, but these days, many people are also getting Rituo.”

When their skin looks duller and less resilient than before, many people first think of skin boosters.

Among them, Rejuran is a representative regenerative skin booster that has been consistently chosen for many years, while Rituo has recently been attracting attention as a new option for supporting the dermal environment.

Both treatments aim to help the skin recover in a healthier condition, but their approaches are somewhat different.

Today, I will explain how to distinguish between Rejuran and Rituo, and which treatment may be more suitable for different skin conditions.

Table of Contents

1. Why skin becomes thin and dull

2. Rejuran helps activate the skin’s recovery signals

3. Rituo supports the dermal environment

4. How should you choose between Rejuran and Rituo?

1. Why Skin Becomes Thin and Dull

As we age, the skin gradually becomes thinner and drier.

Skin that used to look smooth when makeup was applied may begin to flake or look uneven at some point, and fine lines may become more noticeable as the day progresses.

These changes are not simply caused by applying too little moisturizer.

They result from a decline in the density and regenerative capacity of the dermal layer, along with weakened barrier function that reduces the skin’s ability to retain moisture.

Frequent laser treatments, strong exfoliation, sun exposure, lack of sleep, and repeated stress can cause the skin to become fatigued more quickly.

Although these changes may appear as dryness or fine lines on the surface, the skin’s ability to recover from within is often reduced.

Therefore, this type of skin needs more than care that simply moisturizes the surface. It requires treatment that creates an environment in which the skin can recover again.

This criterion is also important when choosing a skin booster.

Rather than focusing only on what ingredient is introduced into the skin, you should first examine the current condition of your skin.

2. Rejuran Helps Activate the Skin’s Recovery Signals

Rejuran is a representative regenerative skin booster based on PN, or polynucleotides.

Its key role is to deliver recovery signals to the skin and help a damaged skin environment resume a normal regenerative process.

Put simply, it can be viewed as a treatment that switches the signals back on so that tired skin can recover on its own.

This is why Rejuran may be considered for people whose skin has become sensitive and thin, who experience severe dryness from within, or who have developed more fine lines.

When the skin barrier is weakened, the skin can quickly become dry no matter how much moisturizer is applied to the surface, and it may easily become red or sensitive even in response to minor irritation.

In such cases, Rejuran can be an option to help improve skin condition and the appearance of fine lines and texture.

However, Rejuran is different from a filler, which directly adds volume.

Rather than being a treatment that immediately makes the face look fuller, it encourages gradual changes toward healthier skin.

For this reason, instead of expecting every change after a single treatment, it is important to plan repeated treatments and maintenance according to your current skin condition.

3. Rituo Supports the Dermal Environment

Rituo is discussed within the same skin booster category as Rejuran, but its approach is somewhat different.

While Rejuran is closer to activating the skin’s regenerative signals, Rituo is more focused on supporting the dermal environment.

Rituo is known as a treatment that uses ECM components derived from acellular allogeneic dermis.

ECM refers to the extracellular matrix environment containing components that form the skin’s structure, such as collagen, elastin, and hyaluronic acid.

As a simple analogy, if Rejuran gives skin cells the signal to “recover again,” Rituo can be viewed as a treatment that supports the underlying structure of weakened skin.

Therefore, Rituo may be considered for people whose skin is thin and dull and who have a strong sense that their dermal density has decreased due to frequent treatments or aging.

It is often described as helping add moisture and radiance to the skin while supporting the firmness of the dermal layer.

Information about Rituo also explains that, while existing skin boosters tend to “induce” regeneration, Rituo “directly supplements” skin components and creates an environment for regeneration.

Of course, Rituo is not automatically suitable for every skin type.

The injection depth, skin thickness, risk of an embossed appearance, and possibility of swelling must be considered, and the intensity and scope of treatment should be determined carefully for people with very sensitive skin.

Ultimately, Rituo should not be chosen simply because it is a popular skin booster. It is important to assess the current dermal environment before applying it.

4. How Should You Choose Between Rejuran and Rituo?

Many people ask which is better, Rejuran or Rituo.

However, I do not say that one is always better than the other.

This is because the two treatments have somewhat different purposes.

If your skin is sensitive, becomes red frequently, has a weak barrier, and repeatedly experiences dryness from within, a treatment that supports the skin’s recovery signals, such as Rejuran, may be needed first.

On the other hand, if your skin has become thinner and less dense and feels generally dull and lacking in resilience, you may consider an approach like Rituo that supports the dermal environment.

Some people may need both treatments.

This may be the case when the skin barrier is weakened and its ability to recover has declined, while the dermal layer also lacks firmness.

In such cases, rather than insisting on just one treatment, it is better to proceed in stages according to the condition of the skin.

First, determine whether the skin is in a condition that can tolerate stimulation. If necessary, you may restore its condition with Rejuran before continuing with dermal support through Rituo.

Alternatively, the two treatments may be performed together depending on skin thickness, dryness, fine lines, and the degree of loss of elasticity.

What matters is not “which treatment is more popular these days.”

The important thing is to distinguish whether your skin currently needs recovery signals or structural support.

In Closing

Both Rejuran and Rituo are skin boosters that may help promote healthier-looking skin.

However, the direction of the two treatments is different.

Rejuran is closer to a treatment that activates the skin’s recovery signals, while Rituo is closer to a treatment that supports the dermal environment and replenishes the skin’s underlying foundation.

Not everyone with thin and dull skin needs the same treatment.

You should first determine whether the main issue is dryness from within, a weakened barrier, fine lines accompanied by loss of elasticity, or decreased dermal density.

With skin boosters, diagnosis comes before product selection.

After accurately identifying how your skin is aging, the necessary treatments should be applied in the appropriate order to achieve natural and stable changes.

If you are considering Rejuran and Rituo, I recommend developing a plan suited to your current skin condition rather than making a decision based only on trends or reviews.

Thank you for reading this lengthy post.

I am Won-shin Lee, a board-certified dermatologist at Wells Dermatology.

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