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What’s the Difference Between Fillers and Rejuran Healer? Imiseok Dermatology

Limeeseok Theme Dermatology Clinic (Main Branch) · 임이석테마피부과의원 · January 4, 2019

What is Rejuran? It is a healing injection that delivers polynucleotide (PN: Polynucleotide), a bio-complex substance, into the dermis layer of the skin to improve the physiologi...

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This page is an English translation of a Korean Naver Blog archive entry. For exact wording and source context, verify against the Korean archive original and the original Naver post.

Clinic: Limeeseok Theme Dermatology Clinic (Main Branch)

Original post date: January 4, 2019

Translated at: April 25, 2026 at 8:45 AM

Medical note: This translation does not guarantee medical accuracy or suitability for treatment decisions.

What’s the Difference Between Fillers and Rejuran Healer? Imiseok Dermatology image 1

What is Rejuran?

It is a healing injection that delivers polynucleotide (PN: Polynucleotide), a bio-complex substance, into the dermis layer of the skin to improve the physiological conditions inside skin that has aged due to UV exposure or a decrease in the fat layer. It fills thin and sagging skin and increases dermal thickness and overall elasticity, helping the skin barrier regenerate.

What’s the difference between fillers and Rejuran Healer?

Rejuran Healer may look similar to fillers, but its function is completely different. Fillers are a non-surgical method that simply fills in sunken areas of the skin and restores volume when facial fullness has decreased due to aging or rapid weight loss, or when deep wrinkles have formed. Healer, on the other hand, extracts and refines polynucleotide, a biocompatible substance, to improve the physiological conditions inside damaged skin and awaken the skin’s own weakened and atrophied regenerative ability.

What’s the Difference Between Fillers and Rejuran Healer? Imiseok Dermatology image 2

In particular, polynucleotide, the key ingredient of Healer, is a substance made by cutting DNA into a specific standard size. It is heat-resistant, so it is not easily destroyed, and because it is compatible with the human body, it does not cause foreign-body reactions in the skin. Polynucleotide helps activate the skin’s self-healing ability and cares for the dermis layer to stabilize the skin’s internal environment.

Rejuran Healer effects

What’s the Difference Between Fillers and Rejuran Healer? Imiseok Dermatology image 3

· Long-lasting effect

· Improves skin tone and skin texture

· Effective for skin elasticity / fine wrinkles around the eyes

· Regenerates the skin barrier

When Rejuran Healer is needed

· Skin damaged by aging, UV rays, or external irritation

· When fine wrinkles and deep nasolabial folds are a concern

· When the skin is thin and sensitive, making treatment difficult

· Skin that has become unnatural due to repeated cosmetic procedures

· When overall skin improvement and a more youthful appearance are desired

· When improvement in skin texture and skin tone is needed

· When sebum reduction and pore reduction are needed

· Busy office workers who need skin improvement but do not have time to worry about it

Precautions after Rejuran Healer treatment

  1. Mild redness, injection marks, or bruising may occur, but they will disappear within 1–2 days.

  2. After Rejuran Healer treatment, avoid high-temperature places such as saunas.

  3. After Rejuran Healer treatment, avoid excessive massage such as lymphatic massage.

  4. For 2–3 days after Rejuran Healer treatment, avoid stimulating activities such as drinking alcohol and smoking.

Imiseok Theme Dermatology Celebrity Dermatology

Imiseok Theme Dermatology, now in its 24th year since opening, is a “long-running dermatology clinic” visited by 200 outpatients a day. Imiseok Theme Dermatology has a system that enables a wide range of treatments and procedures, including a “laser skin clinic” that treats various skin conditions such as wrinkles and elasticity, melasma and pigmentation, acne treatment, pore reduction and scar removal, redness and rosacea (Rosacea/rosacea) treatment, and hyperhidrosis; a “special clinic” for skin aesthetics such as lifting with Botox and fillers, and skin whitening; a “hair transplant center” for hair loss treatment; and medical skin care.

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Dr. Imiseok, the chief director of Imiseok Theme Dermatology, is already well known in the dermatology medical field. He is renowned for comfortable treatment and is famous for providing one-on-one customized treatment that takes into account the characteristics of each patient’s skin. Most of the patients are regulars or referrals, and it is a clinic frequented by many popular Korean celebrities and actresses.

What’s the Difference Between Fillers and Rejuran Healer? Imiseok Dermatology image 5

What’s the Difference Between Fillers and Rejuran Healer? Imiseok Dermatology image 6

What’s the Difference Between Fillers and Rejuran Healer? Imiseok Dermatology image 7

Sinsa Station Dermatology, Imiseok Theme Dermatology

Phone consultation: 02-3446-1110 / 3446-1131

KakaoTalk consultation: Hair ID thema1 / Skin ID thema2

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