Seocho-dong Rejuran Healer: When Fillers Feel Too Heavy and Wrinkles Get Deeper

Rejuran is a procedure that helps thin skin become thicker again.

Polydeoxyribonucleotide (PN) stimulates collagen synthesis in the dermis,

which increases skin density and thickness so wrinkles fill in from within.

As we age, we first notice that our skin has changed through our expressions. Even making the same facial expression feels like wrinkles are etched more deeply.

Even when you slightly squint around the eyes, the lines are clear, and even when you raise your forehead, the lines remain sharply visible. Not only that, but wrinkles that disappeared quickly when you relaxed your face in your 20s now remain like marks even when your face is at rest.

No matter how much you hydrate the surface with cream, deeply etched lines do not change. Wrinkles form not because of lack of moisture, but because the skin itself has become thinner.

As we age and collagen in the dermis decreases, skin thickness also decreases,

and thinner skin folds more deeply even with the same muscle movement.

When collagen decreases, the dermis becomes thinner and wrinkles get deeper

The dermis accounts for 90% of skin thickness. In this layer, collagen and elastin fibers are interwoven like a net to provide support. Up to your 20s, this structure is dense and firm, but after age 25, collagen decreases by about 1% each year, causing the net to loosen.

When collagen decreases, the overall thickness of the dermis becomes thinner, and because the skin’s supporting strength weakens, the surface folds more deeply when facial muscles move. A thick sheet of paper springs back quickly even if folded, but a thin sheet leaves a clear crease.

When the dermis is thick, the skin returns to its original state with elasticity when you relax your expression, but thinned skin keeps the folded marks. Creams and serums are absorbed only into the stratum corneum on the surface and cannot affect collagen in the dermis.

The regenerative principle behind PN making skin thicker

The key ingredient in Rejuran is polydeoxyribonucleotide. PN extracted from salmon DNA is structurally similar to human DNA, so when injected it is absorbed without foreign-body reaction. This ingredient stimulates fibroblasts in the dermis and works by promoting the synthesis of collagen, elastin, and hyaluronic acid. Because it stimulates cells to produce collagen on their own, natural improvement is possible.

The effect becomes more noticeable 2 to 4 weeks after the procedure rather than immediately after it. Right after PN is injected, fibroblasts are stimulated and begin preparing collagen synthesis, so there is not much visible change on the surface. However, after 2 weeks, newly synthesized collagen begins to accumulate in the dermis, and the skin gradually becomes firmer and thicker.

As the dermis becomes thicker, the folded lines are pushed upward. As the thinned dermis fills back in, the sunken areas rise from within, naturally reducing wrinkle depth. Because the structure itself becomes firmer rather than just smoothing the surface, the effect lasts longer.

Category	Rejuran	Juvelook
Main ingredient	PN (polydeoxyribonucleotide)	PDLLA (poly-D, L-lactic acid)
Mechanism	Induces skin regeneration	Collagen production + volume
Purpose	Increases thickness, improves elasticity	Improves wrinkles + adds volume to sunken areas
Time for results	After 2–4 weeks	After 4–8 weeks
Duration	6 months or more based on 3 sessions	6–12 months

Rejuran works by making the skin thicker, while Juvelook works by adding volume to specific areas while also stimulating collagen.

The process of thickness gradually increasing

over 3 sessions

From 2 weeks after one session, the skin texture starts to change. As newly synthesized collagen accumulates in the dermis, the skin gradually fills in, fine lines around the eyes become shallower, and pores also appear smaller, but wrinkles are not yet fully improved. When you receive 3 sessions at 2- to 3-week intervals, the effect accumulates.

While fibroblasts stimulated by the first session are producing collagen, receiving the second session adds new stimulation and increases synthesis further. Repeating this through the third session continuously increases dermal thickness, resulting in a clearer wrinkle-improving effect.

Once the skin becomes thicker, it does not easily become thin again, so based on 3 sessions, the effect lasts 6 months or more. Embossing may appear for 1 to 2 days after the procedure, but it can be covered with makeup, and because this is not a procedure that peels or wounds the skin, you can return to daily life immediately.

Rejuran is a procedure that improves wrinkles by making thin skin thicker. Because the PN ingredient stimulates fibroblasts in the dermis and induces collagen synthesis, the skin fills from within. If you are concerned about wrinkles caused by thin skin, such as fine lines around the eyes or forehead wrinkles, if wrinkles do not improve even when you moisturize with cream, or if fillers feel too heavy and you want a firmer result through a natural approach, you may consider Rejuran Healer.

Seoul, Seocho-gu, Gangnam-daero 415, Daedong Building, 10th and 11th floors 02-5337-4842 Seocho-dong Rejuran Healer Gangnam Toxnfill pursues healthy beauty based on genuine products, proper amounts, and sincerity.

Seocho-dong Rejuran Healer: When fillers feel too heavy and wrinkles get deeper Seocho-dong Rejuran Healer: When fillers feel too heavy and wrinkles get deeper

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