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Jamsil Rejuran Is Not a Procedure You Have to Endure in Pain

You&I Skin Clinic Jamsil · 닥터팽의 피부 좋아지는 이야기 · November 29, 2025

Jamsil Rejuran, it is not a procedure you have to endure in pain ​ ​ 'Rejuran is originally a painful injection, so if I put up with the pain, the effect will be good, right? ​ And...

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This page is an English translation of a Korean Naver Blog archive entry. For exact wording and source context, verify against the Korean archive original and the original Naver post.

Clinic: You&I Skin Clinic Jamsil

Original post date: November 29, 2025

Translated at: April 20, 2026 at 6:10 PM

Medical note: This translation does not guarantee medical accuracy or suitability for treatment decisions.

Jamsil Rejuran, it is not a procedure you have to endure in pain

Jamsil Rejuran Is Not a Procedure You Have to Endure in Pain image 1

'Rejuran is originally a painful injection, so

if I put up with the pain, the effect will be good, right?

And I heard the face gets bumpy after the procedure.

How long does it take for that to go away?'

Because Rejuran pain has become such a well-known topic, some people even say it feels like pain from another world(?)—but it seems like you only get the effect if you suffer through it.

These days, since there are ways to reduce the pain, that is no longer the case. But there was a time when you truly had to endure the pain, and you could sense a quiet kind of madness(?) in the eyes of people who said, 'It hurts, so it’s Rejuran!' while hoping for results.

However, the idea that it is more effective the more it hurts, or that it only works if you feel a lot of pain, is a major misunderstanding.

So today, let’s look at ways to reduce the pain of the Rejuran procedure, as well as the skin reactions that can appear after the procedure.

Jamsil Rejuran,

it is not a procedure you have to endure in pain

  • Ways to reduce Rejuran pain

  • Skin reactions that can appear after the procedure

Jamsil Rejuran

Ways to reduce Rejuran pain

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Rejuran is a procedure that helps skin regeneration by directly injecting polynucleotide (PN), a component extracted from salmon, into the dermis layer of the skin.

However, because the dermis is a shallow layer close to the skin surface, stimulation is inevitable during injection, and because PN itself has a high viscosity, pressure is generated during injection, which causes pain.

So if these issues are addressed, the conclusion is that the pain can be reduced.

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That is exactly 'Rejuran HB PLUS.'

First of all, it contains lidocaine, a local anesthetic ingredient, so the anesthetic effect begins the moment it is injected.

In addition, it also contains hyaluronic acid, which appropriately lowers the viscosity of PN and reduces pressure during injection. When the pressure decreases, the pain naturally decreases as well.

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So compared to conventional Rejuran, pain has been reduced by about 53%. You can think of it as roughly cutting the pain in half.

On top of that, hyaluronic acid has excellent moisturizing effects, so you can think of it as adding a dewy, hydrated glow effect to Rejuran.

The pain is reduced, but you can still get the effects of Rejuran, so I hope you no longer judge the results by how much it hurts.

Jamsil Rejuran

Skin reactions that can appear after the procedure

After Rejuran, temporary changes may appear on the skin.

Typical examples include embossing, swelling, and bruising. If they disappear within a few days, they are not side effects, so there is no need to worry too much.

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Embossing phenomenon

First, when the injection site rises up in a white, bumpy way, that is called the embossing phenomenon.

The PN ingredient is in a gel form, so it maintains a certain viscosity. As it enters the skin, it temporarily creates a raised shape.

It is also a sign that the medication has been properly injected into the skin.

Swelling and bruising are also natural skin reactions caused by the injection stimulus.

It is also normal for the injection site to become slightly red or itchy.

Since these are phenomena that appear during the skin regeneration process, you can observe them for about 3 to 5 days.

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Today, we looked at how the pain of the Jamsil Rejuran procedure can be reduced and at the skin reactions that may appear after the procedure.

Rejuran is no longer a procedure you have to endure while holding back pain and tears. It is also not a procedure where the more it hurts, the better the effect.

Since there are now ways to sufficiently reduce the burden of pain, I hope you will first get a proper consultation and diagnosis to see whether it suits your skin condition and improvement goals, and then make your decision carefully.

Thank you. This was You&I in Jamsil.^^

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