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Jamsil Rituo: How Is It Different from Rejuran? Which Should You Get?

You&I Skin Clinic Jamsil · 닥터팽의 피부 좋아지는 이야기 · March 26, 2026

Jamsil Rituo: How Is It Different from Rejuran? Which Should You Get? ​ ​ ​ "What’s the difference between Rituo and Rejuran? ​ People usually talk a lot about Rejuran, so I haven’...

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This page is an English translation of a Korean Naver Blog archive entry. For exact wording and source context, verify against the Korean archive original and the original Naver post.

Clinic: You&I Skin Clinic Jamsil

Original post date: March 26, 2026

Translated at: April 19, 2026 at 6:46 PM

Medical note: This translation does not guarantee medical accuracy or suitability for treatment decisions.

Jamsil Rituo: How Is It Different from Rejuran? Which Should You Get? image 1

"What’s the difference between Rituo and Rejuran?

People usually talk a lot about Rejuran,

so I haven’t heard much about Rituo...

Is Rituo effective too?"

Even people who have gotten some skin boosters often know Rejuran well, but many are not familiar with Rituo.

Rituo and Rejuran are both grouped under the category of skin boosters, but their principles and effects are different.

Since people mostly just hear that both are good, it can be confusing to know exactly how each one is good and which is right for you.

So today, while organizing the principles and features of Jamsil Rituo and Rejuran, I’ll explain in detail what the differences are and in what skin concerns and situations each one is appropriate.

Jamsil Rituo: How Is It Different from Rejuran?

Which Should You Get?

  • The principles and effects of Rituo

  • The principles and effects of Rejuran

  • I don’t know which one to get

Jamsil

The principles and effects of Rituo

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The key ingredient in Rituo can be said to be ECM, or extracellular matrix components.

ECM is a collection of structural elements that support the skin, densely intertwined with components such as collagen, elastin, and hyaluronic acid. Think of it as the foundation that supports skin cells so they can settle in place and function properly.

As we age, or as external stressors accumulate, the collapse of this foundation can be considered a key cause of skin aging.

Jamsil Rituo: How Is It Different from Rejuran? Which Should You Get? image 3

Rituo extracts this ECM from human dermal tissue, refines it, and injects it directly into the skin.

Since it is extracted from human dermis, you may wonder what that means, but because the cellular components that trigger immune reactions are removed and only the ECM structure is refined and retained, there is no need to be afraid(?).

When Rituo is injected, the ECM components first act as a physical support in the dermis. At this stage, you can feel some effect on skin texture and subtle volume.

Then, as the ECM is slowly broken down, it stimulates the surrounding fibroblasts and induces the production of new collagen and elastin.

Jamsil Rituo: How Is It Different from Rejuran? Which Should You Get? image 4

You can think of it as a structure that allows you to feel some change early on while also creating an environment for the skin to regenerate on its own over time.

Because the ingredient pH is designed to be similar to that of actual skin, and the viscosity is not too strong, pain during injection is reduced.

Jamsil Rituo

The principles and effects of Rejuran

The main ingredient of Rejuran is PN (polynucleotide).

It is a DNA-derived substance extracted from salmon, and because its structure is more than 95% similar to human DNA, it has the major advantage of causing very little foreign-body reaction when introduced into the body.

When this PN component is injected into the dermis, it activates fibroblasts, which are responsible for skin regeneration.

The activated fibroblasts then begin working to produce new collagen and elastin.

Jamsil Rituo: How Is It Different from Rejuran? Which Should You Get? image 5

It is mainly effective for improving skin texture, increasing elasticity, reducing pores, and improving mild acne scars.

As skin thickness and density gradually increase and skin elasticity recovers, you can think of it as having a cumulative effect that builds as you receive more treatments.

There are various products, so it can be administered according to the treatment area or purpose.

Examples include the basic Rejuran Healer, Rejuran I for the eye area, and Rejuran S, which focuses on scar regeneration.

Jamsil Rituo: How Is It Different from Rejuran? Which Should You Get? image 6

In the case of Rejuran HB+, local anesthetic ingredients and hyaluronic acid are additionally included, so pain during injection is reduced and the moisturizing effect is somewhat higher, making it a product widely used these days.

Jamsil Rituo

I don’t know which one to get

First, before the explanation, there is no conclusion that one of the two is better. The choice simply depends on your current skin condition and your main concerns.

I’ve briefly organized the differences between the two below, so please refer to the table.

Jamsil Rituo: How Is It Different from Rejuran? Which Should You Get? image 7

First, let’s look at cases where Rituo may be more effective.

Jamsil Rituo: How Is It Different from Rejuran? Which Should You Get? image 8

Since it essentially starts by supplying the components that make up the skin, it is a good fit when skin aging has progressed to some extent.

In particular, it is worth considering first when fibroblast activity is judged to have decreased, especially after the mid-40s.

It is also a good option for those who want results to appear relatively quickly or who are sensitive to pain.

Next, let’s look at cases where Rejuran may be a better fit.

Jamsil Rituo: How Is It Different from Rejuran? Which Should You Get? image 9

It is well suited for cases where the main goal is to boost the skin’s own regenerative power or for those who need recovery from mild acne scars.

It is also good for those who want to gradually improve elasticity and natural-looking volume.

If you want focused care for specific areas such as the eye area, under the eyes, or the neck, the wide range of product options is another advantage.

If pain is a concern, choosing an HB+ product can substantially reduce discomfort.

To summarize Jamsil Rituo and Rejuran in one sentence:

Rituo directly replenishes the skin structure first to create the foundation for regeneration, while Rejuran works by sending signals to the cells in the skin to induce self-regeneration.

In the end, the goal is the same, but the starting point and path are different.

Jamsil Rituo: How Is It Different from Rejuran? Which Should You Get? image 10

Whether it is Rituo, Rejuran, or anything else, if you need treatment, I recommend first getting a precise check of your current skin condition.

And if you receive treatment from a place that carefully finds the method that suits you and helps you achieve good results, I believe you can expect satisfying outcomes.

Thank you. This was U&I in Jamsil.^^

< How to find a good dermatology clinic in Jamsil? >

< U&I Jamsil Clinic Hours >

Weekdays: am 10:00 ~ pm 08:30

Saturday: am 10:00 ~ pm 05:00

(Treatment without lunch break)

< Directions >

U&I Clinic Jamsil branch is

located in the Lotte World Wellbeing Center.

Jamsil Rituo: How Is It Different from Rejuran? Which Should You Get? image 11

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