[Dr. Bellevue Column 102] Rejuran HB Plus with (?) No Pain! The Standard of Cellular Healing Proposed by Dr. Bellevue

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The weather is extremely hot these days. Please be sure to take care of your health during the summer.

These days, noticeably more people are enjoying running crews and outdoor exercise.

Although these are good habits for your health, from a dermatological perspective, it is easy to overlook the fact that outdoor running can actually accelerate skin aging.

Exposure to strong UV rays and fine dust outdoors, along with the loss of moisture that occurs as sweat dries during exercise, can easily diminish the buffering capacity within the dermal layer.

As collagen and elastin in the dermal layer decrease, the balance of the skin ecosystem can be disrupted and its self-renewal capacity may decline rapidly.

During this period, even the best moisturizer may simply sit on the surface, while the skin becomes easily flushed and loses elasticity, settling into a state of chronic fatigue. To firmly restore unstable skin health, surface-level moisture alone is far from sufficient. A structural approach that restores cellular metabolic function within the dermis should be considered.

From the perspective of rebuilding this dermal ecosystem, I believe Rejuran HB Plus is highly beneficial from a cellular nutrition standpoint. The key to this treatment lies in the organic combination of polynucleotides, a highly purified regenerative active ingredient extracted from salmon DNA, and hyaluronic acid, which regulates moisture within human tissue. Conventional Rejuran does not contain hyaluronic acid.

Polynucleotides injected into the dermal layer help repair damaged genetic structures and activate fibroblasts, setting the skin’s own self-renewal capacity in motion from its foundation. This creates the basis for the thinned, weakened dermis to become thicker again and for the skin barrier to be strengthened from within.

PN (polynucleotide) is a heat-stable, highly biocompatible DNA fragment derived from salmon. Its ability to induce the proliferation of dermal cells (fibroblasts) and promote the synthesis of collagen and elastic fibers (elastin), thereby strengthening the skin barrier, has been demonstrated through various papers and clinical studies.

The hyaluronic acid combined with it creates an optimal moisture environment in real time so that regenerating cells can remain active without becoming fatigued. When hyaluronic acid, which draws in hundreds of times its own volume in water, forms a clear moisture-buffering zone within the dermis, dry spaces between cells are filled, and the dermis’s metabolic functions—including nutrient delivery and waste removal—quickly return to their normal course.

Conventional Rejuran Healer consists only of PN, so the procedure may be more painful, and the sensation of immediate moisture replenishment may be less noticeable at first. In contrast, Rejuran HB Plus is a product formulated with both PN, which supports regeneration, and hyaluronic acid (HA), which has excellent moisturizing properties.

The synergy between these two ingredients goes beyond simply adding moisture. It creates an independent cellular ecosystem in which the skin can retain moisture on its own and defend its barrier.

This type of structural restoration is highly suitable for people whose skin has become thin and sensitive due to frequent laser treatments, as well as patients who experience chronic internal dryness because their oil-moisture balance is easily disrupted by seasonal changes. As the density of the entire dermal layer is neatly restored, rough texture and fine lines may improve, while a clear, luminous complexion originating from cellular health emerges at the surface. Because this process corrects the nutritional balance of the cells, the depth of elasticity becomes more stable over time.

"Hyaluronic acid supplies moisture immediately, while PN improves the dermal environment over the long term, creating excellent synergy for addressing internal dryness and reducing fine lines."

The most reliable way to manage skin aging is to normalize the environment within the disrupted dermis and build its capacity to recover on its own. Precise cellular healing that controls irritation and awakens the restorative capacity of the dermal ecosystem. At Bellevue Clinic near Gangnam Station, where the dermal density and degree of damage are accurately assessed for each patient and customized skin boosters are prescribed with confidence, we invite you to comfortably experience a healthy transformation in your skin’s natural condition—one that builds transparently, without exaggeration.

All procedures may cause side effects such as swelling, bruising, or erythema depending on the individual, so sufficient consultation with a physician is required.

For office workers who have difficulty finding time on weekdays because of their busy schedules, Bellevue Clinic near Gangnam Station provides regular appointments on Sundays and public holidays to make weekend care more convenient. However, please note that the clinic is closed every Wednesday for its regular day off when arranging your schedule. Even in July, the most tiring month of the four seasons, take care of clear and healthy skin. Thank you~!

"Focused on specialized skin diagnostics"

Bellevue Clinic

With the Mark-Vu skin diagnostic examination, you can check various skin concerns at once—including texture, pigmentation, pores, wrinkles, skin tone, dark circles, radiance, redness, melanin, sebum, and acne-causing bacteria—that may be difficult to identify with the naked eye.

Bellevue Clinic scientifically analyzes the skin, makes a final diagnosis of the necessary treatments when appropriate, and strives to provide the most effective and helpful treatments for each patient through kind and detailed consultations.

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💎Bellevue Clinic💎

• Use of authentic products in the correct amounts

• Experienced medical professionals with many years of treatment experience

• Appointments available on Sundays and public holidays

• Customized treatments after Mark-Vu skin diagnostics

🌸Botox. Fillers. Thread lifting. Lifting. Obesity care

🌸Scars. Pores. Various types of pigmentation. Acne. Hair removal

🌸Contour injections. Core Sculpt. Noble Shape.

HPL. V-OLET injections

🌸Diet medication prescriptions after body composition analysis

🌸Prescriptions for hair-loss medication and Viagra

📱Treatment inquiries and reservations

02-533-1200

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