AI-translated archive post

Hongdae Lituo vs. Rejuran Comparison: Effects, Pain, and How Long They Last

차이의원 · 아름다움의 차이, 차이의원입니다. · November 19, 2025

Hello, I’m Dr. Jo Wonjin, and I’ve been seeing patients for 10 years. Doctor, what’s the difference between Rejuran and Lituo? I’m not sure which one is right for me. As the weathe...

AI translation notice

This page is an English translation of a Korean Naver Blog archive entry. For exact wording and source context, verify against the Korean archive original and the original Naver post.

Clinic: 차이의원

Original post date: November 19, 2025

Translated at: April 20, 2026 at 6:15 PM

Medical note: This translation does not guarantee medical accuracy or suitability for treatment decisions.

Hello, I’m Dr. Jo Wonjin, and I’ve been seeing patients for 10 years.

Hongdae Lituo vs. Rejuran Comparison: Effects, Pain, and How Long They Last image 1

Doctor, what’s the difference between Rejuran and Lituo?

I’m not sure which one is right for me.

As the weather gets drier, many people find themselves weighing these two procedures.

Their names are similar, and both are said to improve skin condition, so it’s only natural to get them mixed up.

Under the topic of Hongdae Lituo vs. Rejuran comparison, including effects, pain, and how long they last,

I’ll explain the key differences between the two procedures and help you understand which one may be the better choice for you.

Hongdae Lituo vs. Rejuran Comparison: Effects, Pain, and How Long They Last image 2

Table of contents

  • How are Lituo and Rejuran different in effect?

  • Pain and duration of effect

  • Is the procedure safe?

  • Which procedure is right for me?

Hongdae Lituo vs. Rejuran comparison How are Lituo and Rejuran different in effect?

In simple terms, Rejuran sends a regeneration signal to our skin.

Its main ingredient, PN, is closer to a restorative procedure that creates a good environment for tired skin cells to start working again.

It focuses on building up the skin’s own strength.

That is why Rejuran is excellent for improving the skin’s basic resilience.

It provides a regenerative effect for people whose skin is thin and very dry, whose makeup sits unevenly and whose skin looks rough, or whose skin barrier is weak and prone to redness.

Hongdae Lituo vs. Rejuran Comparison: Effects, Pain, and How Long They Last image 3

Lituo, on the other hand, is a little different.

It is more of a supplementation concept in which material is directly added.

It finely breaks down ingredients that are the same as those in our skin tissue,

and works by directly replenishing collagen and elastin that have been lost through aging.

You can think of it as being closer to an all-in-one approach.

Because it supplements the skin with actual building blocks.

It is strong when it comes to making the skin feel firmer, especially when elasticity has declined and pores appear stretched vertically,

or when dryness and fine lines are visible together.

The difference is between giving the skin the power to recover on its own and adding back the materials that have disappeared.

Hongdae Lituo vs. Rejuran Comparison: Effects, Pain, and How Long They Last image 4

Hongdae Lituo vs. Rejuran comparison Pain and duration of effect

This is the part most patients are curious about.

Honestly, Rejuran hurts.

Among skin boosters currently available, it is one of the more painful ones.

Also, its duration of effect is relatively short, around 2 to 3 months, so repeated treatments may be necessary, which can be burdensome from a patient’s perspective.

Hongdae Lituo vs. Rejuran Comparison: Effects, Pain, and How Long They Last image 5 I attached a post at the bottom in case you are curious about painless Rejuran in the photo.

Lituo addresses both of these drawbacks to a large extent.

Compared with Rejuran, the procedure is less painful, and above all,

when the recommended number of sessions (usually 3) is completed, the duration of effect is relatively long, at 6 months to more than 1 year.

Rather than stimulating the body to make collagen, it adds the tissue itself, so the effect lasts longer.

Hongdae Lituo vs. Rejuran Comparison: Effects, Pain, and How Long They Last image 6 Reference to the manufacturer’s clinical results for Lituo

Hongdae Lituo vs. Rejuran comparison Is the procedure safe?

Rejuran is injected into the superficial layer of the skin.

So for a few days after the procedure, raised embossing marks may remain.

This is not really a side effect, but a natural part of the process.

Since Lituo uses components derived from human tissue,

it is relatively free from the risk of nodules, which is a concern with other collagen injections (PDLLA), and so on.

Hongdae Lituo vs. Rejuran Comparison: Effects, Pain, and How Long They Last image 7

However, for both procedures, the doctor’s experience is absolutely crucial.

For Rejuran, skill is needed to make the embossing uniform,

and for Lituo, it is important to distribute and inject it in a way that matches the desired direction: carefully with a hand syringe for part of it, and with a cannula for the remaining amount into a deeper layer.

Please refer to the post below for that.

※ If you are considering Lituo, please be sure to read the post below before getting it. I have written down why it may not work for some people.

In fact, for both procedures, the satisfaction level depends on the technique used to carefully inject the tissue into the correct skin layer,

so I recommend receiving treatment from a doctor with strong hands-on skill and extensive experience.

Hongdae Lituo vs. Rejuran comparison Which procedure is right for me?

Here is the simple summary.

Who needs Lituo

  • You want an all-in-one effect that addresses elasticity, pores, dryness, and skin texture at once.
  • You prefer something less painful and want a longer duration of effect.
  • Fillers feel burdensome, but you want a natural firming effect.

Who needs Rejuran

  • Your skin is thin and sensitive, so you need to build up its basic resilience first.
  • Improving the oil-water balance and skin texture is urgent.
  • Even if you have to accept pain and shorter intervals, you want to focus on skin regeneration.

Hongdae Lituo vs. Rejuran Comparison: Effects, Pain, and How Long They Last image 8

In the end, a trustworthy clinic is one that provides careful consultation and also leaves patients highly satisfied after the procedure.

I’ve written a post about how to find a good clinic, so please be sure to read it.

At the very least, it should help you avoid being overcharged at a dermatology clinic.

The important thing is not which is better between Lituo and Rejuran.

What matters in the end is getting an accurate diagnosis of whether your skin currently needs restoration or supplementation.

I hope you find a clinic that clearly explains the differences between these two procedures and honestly recommends the treatment that matches your skin condition.

Thank you, this was Jo Wonjin.

Hongdae Lituo vs. Rejuran Comparison: Effects, Pain, and How Long They Last image 9

< Still want to know more about Rejuran? >

Depending on how Rejuran is administered, its effects can vary dramatically. Please refer to the post below.

Hongdae Lituo vs. Rejuran Comparison: Effects, Pain, and How Long They Last image 10

Hongdae Lituo vs. Rejuran Comparison: Effects, Pain, and How Long They Last image 11

Continue browsing

Keep exploring this clinic's public source trail

Return to the source archive for more translated posts, or open the Korean clinic profile to compare other public channels.