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What Effects Can You Expect from Lip Rejuran?

You&I Clinic Hongdae Sinchon · 닥터다람의 예뻐지는 피부비결 · February 24, 2026

If you get Lip Rejuran, what effects can you expect? "Do people get Rejuran in the lips too?" At first, that may feel a little unfamiliar. Rejuran is mostly received for the skin,...

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This page is an English translation of a Korean Naver Blog archive entry. For exact wording and source context, verify against the Korean archive original and the original Naver post.

Clinic: You&I Clinic Hongdae Sinchon

Original post date: February 24, 2026

Translated at: April 20, 2026 at 4:07 AM

Medical note: This translation does not guarantee medical accuracy or suitability for treatment decisions.

If you get Lip Rejuran,

what effects can you expect?

"Do people get Rejuran in the lips too?"

At first, that may feel a little unfamiliar. Rejuran is mostly received for the skin, so when people hear that it can be used on the lips, they may find it unusual.

But in fact, lips also change as we age.

It is not simply a loss of volume; the tissue itself begins to age.

Lip Rejuran can help with these changes.

Today, let’s talk one by one about how lips change with age, how Rejuran works, and what to know after the procedure.

What effects can you expect from Lip Rejuran?
1. Do lips also age? 2. What are the effects of Lip Rejuran? 3. Aftercare and precautions
  1. Do lips also age?

Lip Rejuran

When people talk about lip aging, most first think of volume loss.

In fact, there is a change that is felt even before that.

Lips become dry, the texture becomes rough, and fine lines begin to appear.

What Effects Can You Expect from Lip Rejuran? image 1

There is a reason for this change. The skin of the lips is much thinner than other areas of the face.

It is also an area without sebaceous glands, so it cannot produce its own oil.

As collagen and elastin decrease with age, this thin tissue is affected more quickly.

Its ability to retain moisture declines, the surface becomes rough, and fine lines begin to form.

What Effects Can You Expect from Lip Rejuran? image 2

The border of the lips also becomes less distinct, and the overall impression changes into one that looks less vibrant.

This process is different from a volume issue.

Rather than simply filling volume, what is needed more is a direction that regenerates the lip tissue itself.

  1. What are the effects of Lip Rejuran?

The main ingredient of Rejuran, PN, works by stimulating fibroblasts through cell signaling.

In this process, collagen and elastin are newly produced.

Rather than directly adding volume, it induces regeneration of the lip tissue itself.

What Effects Can You Expect from Lip Rejuran? image 3

So after Lip Rejuran, two main changes appear.

One is hydration. PN stimulates cell regeneration, which improves the lip tissue’s ability to retain moisture.

Many people feel that their lips become more moisturized right after the procedure.

The other is improvement in texture. Fine lines on the lip surface are reduced, and the overall surface becomes smoother.

This is especially noticeable for people whose lip products used to crack on application or whose vertical lines stood out.

Let’s look at a research paper that examined a procedure on the lips.

What Effects Can You Expect from Lip Rejuran? image 4

Results were followed up for up to 6 months after Lip Rejuran treatment.

The left photo is before treatment, and the right photo shows the lips 6 months after treatment.

What Effects Can You Expect from Lip Rejuran? image 5 What Effects Can You Expect from Lip Rejuran? image 6

It was confirmed that the surface texture became smoother and the overall appearance changed to one that looked more moisturized and vibrant.

The effect was seen to last up to 6 months after the procedure.

  1. Aftercare and precautions after Lip Rejuran treatment

The lips are one of the most frequently moved areas of the face.

So right after the procedure, there are a few things to be careful about.

On the day of treatment, try to avoid actions that open the mouth widely or make intense facial expressions, and smoking should be avoided for about 72 hours, as it may interfere with ingredient absorption and the regeneration process.

What Effects Can You Expect from Lip Rejuran? image 7

Right after the procedure, there may be some swelling and a slight stinging sensation.

This is a natural phenomenon that occurs during the process of the ingredients settling in, and in most cases it goes down within a day or two.

To maintain the effect for longer, it is important to receive it periodically.

You may feel a change even after one session, but if you repeat treatments at 3- to 4-week intervals, collagen regeneration accumulates and the results become more noticeable.

Today, we talked about what effects you can expect from Lip Rejuran.

Rather than increasing lip volume like filler, Lip Rejuran helps improve lips that are dry and have fine lines.

As the lips regenerate, a natural sense of volume can appear.

If your lips are currently more dry than lacking volume, Rejuran may be more suitable than filler.

I hope you carefully review your concerns and skin condition first, and then decide on the treatment that is needed for your lips.

Thank you. This was UNNI Hongdae Sinchon^^

<The story of the Hongdae Sinchon branch over the past 10 years>

<Directions to UNNI Clinic Hongdae Sinchon Branch>

What Effects Can You Expect from Lip Rejuran? image 8

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