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What Are the Effects of Radiesse for Back-of-Hand Wrinkle Treatment?

You&I Skin Clinic Yeongdeungpo · 냥닥터의 피부 시술 이야기 · March 15, 2026

Radiesse Back-of-Hand Wrinkle Treatment What are the effects? "The wrinkles on the back of my hands are bothering me.. If I get Radiesse, will the wrinkles improve?" Many people ha...

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This page is an English translation of a Korean Naver Blog archive entry. For exact wording and source context, verify against the Korean archive original and the original Naver post.

Clinic: You&I Skin Clinic Yeongdeungpo

Original post date: March 15, 2026

Translated at: April 20, 2026 at 2:18 AM

Medical note: This translation does not guarantee medical accuracy or suitability for treatment decisions.

Radiesse Back-of-Hand Wrinkle Treatment

What are the effects?

"The wrinkles on the back of my hands are bothering me.. If I get Radiesse, will the wrinkles improve?"

Many people have tried various treatments for the face, but are not sure what to get for the hands.

That is because the back of the hands has not received as much attention as the face.

The best-known treatment for it seems to be Radiesse.

Today, I’d like to talk honestly about what kind of treatment Radiesse is and what effects it has on back-of-hand wrinkles, based on actual clinical research.

What Are the Effects of Radiesse Back-of-Hand Wrinkle Treatment?
​1. How should back-of-hand treatment be approached? ​2. What is Radiesse back-of-hand wrinkle treatment? ​3. What are the improvement effects of Radiesse on the back of the hand?​
  1. Radiesse

How should back-of-hand treatment be approached?

For those concerned about aging on the back of the hands, the first thing they often look for is a moisturizing cream.

It may help a little with skin texture, but aging on the back of the hands is not just a matter of skin texture.

That is because the issue is not only back-of-hand wrinkles, but also the visibility of tendons and blood vessels.

What Are the Effects of Radiesse for Back-of-Hand Wrinkle Treatment? image 1

The essence of these changes is volume loss.

As we age, the fat in the subcutaneous tissue decreases, and the structures that supported the skin become thinner, causing the tendons and blood vessels underneath to become visible.

In facial terms, this is similar to how hollow cheeks make the cheekbones stand out more.

So aging on the back of the hands should be approached by filling in volume along with improving skin texture.

  1. What is Radiesse back-of-hand wrinkle treatment?

Radiesse is a filler made from calcium hydroxylapatite.

What Are the Effects of Radiesse for Back-of-Hand Wrinkle Treatment? image 2

Calcium hydroxylapatite is a substance similar to the components that make up our bones and teeth.

It has high biocompatibility and settles stably within the tissue.

The filler is injected into the space between the subcutaneous tissue of the back of the hand and the superficial fascia.

When Radiesse fills this space, a layer is created over the tendons and blood vessels, so the prominent structures are naturally covered.

That is not the end of it.

After being injected, Radiesse begins stimulating the surrounding fibroblasts over time.

When fibroblasts are activated, new collagen is produced.

What Are the Effects of Radiesse for Back-of-Hand Wrinkle Treatment? image 3

This collagen gradually thickens the tissue of the back-of-hand skin, working in a way that helps volume last more firmly.

In other words, Radiesse is a method that can be expected to provide both immediate volume recovery right after injection and tissue regeneration effects that build over time.

  1. What are the improvement effects of Radiesse on the back of the hand?

So naturally, you may be wondering how effective it actually is. Let’s look at the research.

What Are the Effects of Radiesse for Back-of-Hand Wrinkle Treatment? image 4

This study evaluated the volume restoration effects after applying Radiesse to the back of the hand.

At four institutions in Germany, 101 participants were divided into a treatment group and an untreated control group, and the results were compared at 3 months and 6 months.

The photo below shows a 59-year-old woman who participated in the study before treatment (A) and after 3 months (B) and 6 months (C).

What Are the Effects of Radiesse for Back-of-Hand Wrinkle Treatment? image 5

The back of the hand, where tendons were visibly prominent, was naturally filled in, and the wrinkles were also improved.

Improvement was confirmed in 89% of hands at 3 months after treatment, and 75% still maintained improvement at 6 months.

What Are the Effects of Radiesse for Back-of-Hand Wrinkle Treatment? image 6

There was a statistically significant difference compared with the control group.

An important point is that there was no effect on hand function after the procedure.

What Are the Effects of Radiesse for Back-of-Hand Wrinkle Treatment? image 7

Because it is injected precisely into the space above the tendons, it does not cause discomfort when using the hands.

Side effects were swelling, bruising, and pain, and most naturally subsided within 2 weeks.

Today, we looked at Radiesse back-of-hand wrinkle treatment.

For a long time, the back of the hands has been a blind spot in aging management. It has not received as much attention as the face.

Radiesse is not simply about filling wrinkles, but also about restoring volume to the back of the hands.

However, because the injection site and volume design must be determined by directly examining the structure of the back of the hand and the degree of aging,

I recommend making your decision after 충분히 consulting with an experienced medical professional.

Thank you. This was Yeongdeungpo You&I^^

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