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Can IriJuran Improve Dark Circles and Under-Eye Wrinkles?

You&I Skin Clinic Yeongdeungpo · 냥닥터의 피부 시술 이야기 · March 31, 2026

IriJuran Dark Circles Can it improve under-eye wrinkles? "If I get IriJuran injections, will my dark circles really get better?" When looking into under-eye treatments, this is the...

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This page is an English translation of a Korean Naver Blog archive entry. For exact wording and source context, verify against the Korean archive original and the original Naver post.

Clinic: You&I Skin Clinic Yeongdeungpo

Original post date: March 31, 2026

Translated at: April 19, 2026 at 3:16 PM

Medical note: This translation does not guarantee medical accuracy or suitability for treatment decisions.

IriJuran Dark Circles

Can it improve under-eye wrinkles?

"If I get IriJuran injections, will my dark circles really get better?"

When looking into under-eye treatments, this is the question people ask most often.

I know it makes sense to wonder whether IriJuran is really designed for the under-eye area, and whether it actually has much effect on dark circles or under-eye wrinkles.

So today, I’ll explain honestly how IriJuran works in the under-eye area, how much change has been confirmed in studies, and which under-eye concerns it may suit best.

Can IriJuran improve dark circles and under-eye wrinkles?
​1. How does it work under the eyes?​2. What effects have been confirmed in studies?​3. What kind of under-eye concerns is it suitable for?​
  1. IriJuran dark circles How does it work under the eyes?

The skin under the eyes is the thinnest area on the face.

So as we age and collagen decreases, changes become noticeable there faster than in other areas.

Can IriJuran Improve Dark Circles and Under-Eye Wrinkles? image 1

Fine lines appear, and as the skin thins, underlying blood vessels may show through, making the area look like dark circles.

The key ingredient in IriJuran is PN (polynucleotide), a high-purity DNA fragment extracted from salmon.

This ingredient stimulates fibroblast proliferation and collagen synthesis within the skin.

Can IriJuran Improve Dark Circles and Under-Eye Wrinkles? image 2

IriJuran is a product designed specifically for the under-eye area using this PN ingredient.

Compared with Rejuran Healer, which has a higher viscosity, IriJuran has its concentration and viscosity adjusted for the thin skin under the eyes, so it is designed to spread evenly in the dermis without clumping or a foreign-body sensation.

  1. IriJuran dark circles and under-eye wrinkles What effects have been confirmed in studies?

So then, what changes does IriJuran actually make in the under-eye area? There is a clinical study that confirms this, so let’s take a look together.

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This paper studied 42 people ages 25 to 65, injecting PN into the under-eye area and following them for up to 6 months.

The treatment was performed twice at 3-week intervals, and changes in under-eye wrinkles and crow’s feet were measured numerically using the validated FACE-Q assessment tool.

Below is a photo showing changes in the under-eye area before treatment and 3 months after.

Can IriJuran Improve Dark Circles and Under-Eye Wrinkles? image 4

You can see that fine wrinkles under the eyes were reduced and the skin texture became smoother.

Pigmentation also improved, with the dark circles appearing lighter.

The numbers make it even clearer.

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The under-eye wrinkle score improved by an average of 6.5 points at 1 month compared with before treatment, and improved by up to 9.5 points at 3 months.

The crow’s feet score also improved by 6.8 points at 1 month and 10.6 points at 3 months.

What stands out here is that the score improved more at 3 months than at 1 month.

Can IriJuran Improve Dark Circles and Under-Eye Wrinkles? image 6

Normally, the effect of a procedure is best right after treatment and then gradually decreases over time.

The fact that the skin continued improving up to 3 months means that PN promoted collagen regeneration and tissue remodeling within the skin over time.

At the 6-month mark, there was a slight decrease compared with 3 months, but the results were still maintained at a level significantly higher than before treatment.

  1. IriJuran dark circles and under-eye wrinkles What kind of under-eye concerns is it suitable for?

The clinical results are impressive, but they do not apply equally to every under-eye concern.

IriJuran may be a good fit for cases such as:

when fine wrinkles under the eyes are starting to appear,

when the skin has become thinner and dark circles look more noticeable,

or when you feel that the elasticity and texture of the under-eye skin have generally declined.

The study also shows this point.

Can IriJuran Improve Dark Circles and Under-Eye Wrinkles? image 7

The fact that the clearest effect was seen 3 months after the second treatment means that PN’s regenerative effect appears most strongly in early to moderate under-eye aging.

On the other hand, if the under-eye area is deeply hollowed or fat protrusion is pronounced, IriJuran alone may not be enough.

In that case, it is more realistic to consider other methods that can restore volume as well.

As confirmed in studies, IriJuran’s effect on dark circles and under-eye wrinkles is a regenerative change that becomes clearer over time.

Because this is not a method that immediately fills something in, but rather an approach that changes the skin environment, a steady plan is important.

If you’re wondering whether it’s the right option for your under-eye area, I recommend making a plan through a thorough consultation.

Thank you. This was Yeongdeungpo U&I^^

< Criteria for choosing a dermatology clinic in Yeongdeungpo >

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Weekdays: am 10:00 ~ pm 08:30 Weekends: am 10:00 ~ pm 05:00 (No lunch break)

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U&I Clinic Yeongdeungpo Branch is located near Exit 5 of Yeongdeungpo Station.

Can IriJuran Improve Dark Circles and Under-Eye Wrinkles? image 8

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