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Balsan Station Dermatology, One-Week Changes After Rejuran HB

Hongdae Dermatology Skin Clinic 弘大美丽石医院 · ✦뷰티스톤의원 합정역✦ · November 29, 2025

Hello. This is Woo Young-jin from Balsan Station Dermatology. Have you ever felt so frustrated that no matter how diligently you applied expensive creams, the dryness and tightness...

AI translation notice

This page is an English translation of a Korean Naver Blog archive entry. For exact wording and source context, verify against the Korean archive original and the original Naver post.

Clinic: Hongdae Dermatology Skin Clinic 弘大美丽石医院

Original post date: November 29, 2025

Translated at: April 20, 2026 at 6:09 PM

Medical note: This translation does not guarantee medical accuracy or suitability for treatment decisions.

Balsan Station Dermatology, One-Week Changes After Rejuran HB image 1

Hello.

This is Woo Young-jin from Balsan Station Dermatology.

Have you ever felt so frustrated that no matter how diligently you applied expensive creams,

the dryness and tightness deep inside your skin still would not improve?

As the dryness inside the skin gradually eased,

I felt even fine lines becoming softer.

For people who have experienced Rejuran HB,

the first change they usually mention

is exactly this part.

Not from the surface,

but improvement that begins deep within the skin.

Today, based on real experiences, I will summarize the actual effects of Rejuran HB

and the changes in the skin during the week after the procedure. How does it work?

Balsan Station Dermatology, One-Week Changes After Rejuran HB image 2

It works by placing PN (polynucleotide, the key substance that helps skin recovery)

derived from salmon DNA into the dermal layer of the face.

That is why it is commonly called a salmon injection,

but strictly speaking, a salmon injection refers to a PDRN injection,

and Rejuran HB is classified as a PN injection.

For sensitive skin, fine lines, or those struggling with reduced elasticity,

it can be an excellent option. My inner dryness was severe,

but after the procedure I could feel moisture filling in

from inside the skin. In short,

it is a procedure that enhances the skin’s ability to recover on its own

and creates a healthier internal environment. Comparison of effects by injection method

The injection method is broadly divided into two types.

First,

a method in which a medical professional injects by hand.

Second,

a method that uses a dedicated device for injection. Hand injection

Hand injection is a method in which a specialist precisely delivers the medication

to each area of the dermal layer.

Compared with using a device,

the drug loss rate, or loss ratio, tends to be lower.

In simple terms,

if less medication leaks out during the injection process,

you can understand that the actual effectiveness of Rejuran HB

will be better realized. It felt as if each area was treated with great care. When receiving the procedure at Balsan Station Dermatology,

people who wanted hand injection especially paid attention to this loss ratio. Device injection

Device injection is a method that uses a machine

to inject PN ingredients into the dermis.

Compared with hand injection,

the medication is distributed more evenly,

and it has the advantage of easier fine adjustment.

In addition, because the needle is thinner,

the level of pain is lower, which is also a benefit. When I received it with the device,

the pain was almost less than I expected, so it was comfortable. In the end, rather than one being absolutely better,

the key is choosing the method that suits you best. Treatment interval, when effects appear, and duration

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For reference,

the raised marks that appear after Rejuran HB treatment are not simply a side effect,

but also a sign that the medication has been delivered properly

to the correct depth. One of the questions people ask most often is when the effects of Rejuran HB begin to show.

It is one of the questions I hear most often in the consultation room. About two weeks after the procedure,

I could clearly feel that the skin texture had become

noticeably smoother. State immediately after the procedure

It is difficult to expect dramatic changes immediately after the procedure.

Of course, there may be some feeling of improvement even on the day of treatment.

However, because this is very different from the changes that occur as collagen is newly produced over time

and the internal conditions of the skin improve,

it is hard to regard that moment as the effect of Rejuran HB.

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After 2 weeks

About two weeks after the procedure,

you can begin to expect gradual skin improvement.

And between 2 and 4 weeks,

the full effect becomes apparent,

and it generally lasts about 6 months to 1 year. ※ Based on receiving it at least 3 times.

However, after Rejuran HB treatment,

the time when the effect appears and how long it lasts

can vary depending on each person’s skin condition and overall health,

so please keep this in mind.

When you get a consultation at Balsan Station Dermatology,

checking your skin condition in detail

allows for a more accurate prediction of the effect.

(For more details, ▽) Recommended treatment interval

When I explain it this way,

many people ask back,

"Then does that mean I only need to get it once every 6 to 12 months?"

In my opinion, if possible,

it is best to do the first three treatments at one-month intervals,

and after that, to receive maintenance treatments every 3 to 4 months,

so that the effects of Rejuran HB can be maintained for a longer period. I completed three sessions and then maintained it at 4-month intervals,

and I could feel that the firmness was being maintained. The interval can be adjusted depending on your skin condition,

so please use this as a reference without pressure.

People who visit Balsan Station Dermatology

were most satisfied when they managed it with this kind of schedule. Key summary for today

🔹 PN ingredients help restore skin elasticity and relieve internal dryness

🔹 The key is accurate injection into the dermal layer

🔹 Effects begin to appear gradually from 2 to 4 weeks after treatment

🔹 Rejuran HB effects are

stably maintained only after at least 3 sessions

🔹 After Rejuran HB, depending on individual skin condition,

it lasts about 6 months to 1 year

Today, I organized the information related to when the effects

after Rejuran HB treatment begin to appear.

I hope this was helpful, even a little.

If you have any other questions about Rejuran HB,

feel free to leave a comment.

I will answer directly. Thank you for reading.

This was Woo Young-jin from Balsan Station Dermatology.

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