
Hello.
This is Kim Jang-ju from Hwagok-dong Dermatology Clinic.
Are you worried about dry skin and fine lines?
Rejuran, known as the “salmon injection,”
is attracting a lot of attention
for its skin regeneration and elasticity-improving effects.
But once you actually decide to get the procedure,
there are a lot of things people want to know.
When Rejuran’s effects appear.
How much pain there is.
Whether there are side effects.
From now on, I’ll explain everything
about Rejuran in detail.
Please read carefully,
and I hope this helps you make a wise choice.
How does Rejuran work?

The key ingredient in Rejuran is
polynucleotide (PN).
When DNA fragments extracted from salmon
are injected deep into the dermal layer of the skin,
fibroblasts are activated.
As a result, the production of collagen
and elastin increases.
Through this process,
the skin barrier is strengthened,
fine lines improve,
and elasticity is restored.
You can experience a comprehensive anti-aging effect
that also relieves dryness from within.
When do Rejuran’s effects start to show?
There are individual differences,
but most people begin to notice skin changes
about 2 to 4 weeks after the procedure.
The full Rejuran effect appears gradually
over 1 to 3 months.
This is because the regeneration process
inside the skin progresses slowly.
Rather than expecting dramatic changes all at once,
it is best to understand it as a process
of natural improvement over time.
(More detailed information below ▼)
How long do Rejuran’s effects last?
In general, the effects last
about 6 months to 1 year.
At first, it is recommended to receive
about 3 intensive treatments
at one-month intervals.
After that, maintenance treatments
every 3 to 4 months are common.
People who visit Hwagok-dong Dermatology Clinic
can also get more satisfying results
if they continue regular treatment at this interval.
Let me be honest about the pain
Compared with other skin boosters,
Rejuran tends to be somewhat painful.
Because it has to be injected
into the exact depth of the dermal layer,
irritation during the procedure
is unavoidable.
According to people who have had it before,
it is not unbearably painful,
but
they do clearly feel stinging
and pressure.
In particular, Rejuran has a high-viscosity formula,
so when it enters the skin,
more intense pain may be felt
momentarily.
What is the embossing effect?
The small bumpy raised texture
that appears on the skin surface immediately after the procedure
is called embossing.
This is a normal reaction that occurs
as the medication remains in the skin,
so there is no need to worry.
It usually disappears naturally
as it is absorbed over about 2 to 3 days.
How can pain be reduced?
If you are concerned about pain,
it can be eased with the following methods.
- Use of anesthetic cream
Applying it before the procedure
can significantly reduce pain.
- Choosing Rejuran HB
Because it contains hyaluronic acid
and anesthetic ingredients together,
it is much less painful than regular Rejuran.
- Using a microneedle device
Using an injection device with fine needles
can reduce pain even further.
When you consult at Hwagok-dong Dermatology Clinic,
if you ask in advance about pain-relief methods,
you can be guided to the best option
for you.
In conclusion, pain is
to some extent something you have to accept,
but there are various ways to reduce it,
and considering the results after the procedure,
many people judge it to be a level
that is sufficiently tolerable.
Side effects and precautions
Rejuran is known as a relatively safe procedure,
but that does not mean there is no possibility
of side effects at all.
Common reactions include bruising and swelling,
and in rare cases, inflammation or allergic reactions
may occur.
In most cases, recovery happens naturally
within a few days.
Accurate injection is the key

The success or failure of Rejuran treatment
depends on the medical staff’s skill.
It must be injected accurately into the dermal layer,
especially the thin 1 to 2 mm layer,
in order to see the proper Rejuran effect.
If injected too shallowly,
it stays only in the epidermis and the effect is minimal.
On the other hand, if it goes too deep,
it flows into the subcutaneous fat layer,
making it difficult to achieve the desired result.
Therefore, rather than relying only on the quality of the product,
it is important to check whether there are
experienced medical staff who can inject it precisely.
Also carefully look into whether the clinic
goes through sufficient consultation and diagnosis.
When choosing a dermatology clinic in Hwagok-dong,
I recommend checking whether there is medical staff
with abundant procedure experience,
and whether a systematic consultation system
is in place.
How can you maximize Rejuran’s effects?

For the best results,
aftercare is also important.
On the day of the procedure,
avoid washing your face and wearing makeup.
For one week,
avoid high-temperature environments
such as saunas and jjimjilbangs.
Keep up with
sufficient water intake
and strict sun protection.
If you manage it this way,
you can maintain the effects of Rejuran for longer.
At Hwagok-dong Dermatology Clinic,
we also provide detailed guidance on aftercare
n
after the procedure,
so if you have any questions,
please feel free to ask anytime.
Key points
To summarize the Rejuran information shared today:
- An anti-aging treatment using PN ingredients
that improve skin elasticity, skin texture,
and fine lines
-
There is some pain, but various pain-relief methods exist
-
Injecting at the correct depth is the key to effectiveness
If you have any additional questions
about Rejuran,
please leave them in the comments anytime.
I will answer them directly.
Thank you for reading.
This was Kim Jang-ju from Hwagok-dong Dermatology Clinic.

