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Rejuran Effect Differences: Which Skin Type Is Suitable for Healer/HB/Eye? (Q&A)

Hongdae Dermatology Skin Clinic 弘大美丽石医院 · ✦뷰티스톤의원 합정역✦ · April 9, 2026

Hello. This is Beauty’s Doctor, Wi Yeong-jin. When I consult about Rejuran, there are questions I get often. What exactly is Rejuran? What is the difference between Healer and HB?...

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This page is an English translation of a Korean Naver Blog archive entry. For exact wording and source context, verify against the Korean archive original and the original Naver post.

Clinic: Hongdae Dermatology Skin Clinic 弘大美丽石医院

Original post date: April 9, 2026

Translated at: April 19, 2026 at 1:48 PM

Medical note: This translation does not guarantee medical accuracy or suitability for treatment decisions.

Rejuran Effect Differences: Which Skin Type Is Suitable for Healer/HB/Eye? (Q&A) image 1

Hello.

This is Beauty’s Doctor, Wi Yeong-jin.

When I consult about Rejuran, there are questions I get often.

What exactly is Rejuran? What is the difference between Healer and HB? When do the effects appear? How many sessions are needed? Does it hurt?

Rejuran is not a procedure that fills immediately like a filler.

Because it is a treatment that regenerates the skin itself,

it is important to understand both the procedure principle and the process by which the effects appear.

So today, I’ll organize the most common questions about Rejuran procedures,

covering

effects pain recovery number of sessions differences

as well.

  1. What exactly is a Rejuran procedure?

Rejuran is a procedure that injects PN (Polynucleotide), a DNA precursor substance, into the skin.

It was originally developed for

inflammation improvement skin regeneration purposes.

So it is an ingredient that was used in regenerative treatment for

burned skin inflamed skin damaged skin

.

Later, as Rejuran Healer gained popularity, various sub-versions were released.

Rejuran Effect Differences: Which Skin Type Is Suitable for Healer/HB/Eye? (Q&A) image 2 The main ones are

Rejuran Healer Rejuran Eye Rejuran HB

There are three.

In other words, Rejuran gives the skin regeneration signals from within the skin to improve the damaged skin environment,

and should be understood as a skin regeneration treatment.

  1. Differences between Rejuran Healer / Eye / HB

Rejuran Effect Differences: Which Skin Type Is Suitable for Healer/HB/Eye? (Q&A) image 3 Rejuran Healer

→ PN-only ingredient → Focused on cell regeneration → Improves fine lines Rejuran Eye

→ PN-only ingredient → For the eye area only → Improves thin skin Rejuran HB

→ PN + hyaluronic acid → Moisture + regeneration → Improves dry skin

To summarize

Healer / Eye → Regeneration-focused

HB → Regeneration + moisture

HB contains hyaluronic acid, which adds the effect of drawing moisture into the skin.

So it is often chosen for

dry skin thin skin skin with many fine lines

.

  1. What skin concerns is it effective for?

Rejuran is effective for

fine lines reduced elasticity rough skin texture acne scars weakened skin barrier

.

In particular, it helps as a regenerative procedure when

the skin has become thinner fine lines have increased elasticity has decreased

.

For fine lines and reduced elasticity, adding Juvelook SB can improve the effect.

Rejuran → Skin regeneration

Juvelook → Collagen production

Because these two work together.

  1. When do the effects appear?

The effects of Rejuran usually begin to appear gradually about one week after the procedure.

Rather than an immediate change, it is a way for the skin to improve gradually.

Usually, between 2 and 4 weeks,

skin texture improvement fine line improvement elasticity improvement

appear.

After about 3 sessions,

skin density improvement skin thickness improvement

can also be seen.

  1. How long does it last?

The effects of Rejuran last about 2 months.

However, when the effect fades, it does not mean the skin returns completely to how it was before the procedure.

Because skin regeneration accumulates, the more sessions you have, the more the skin condition improves.

So it is often done as an initial 3-session treatment, followed by maintenance treatments.

  1. How many sessions are appropriate?

In general, 3 sessions at 1-month intervals are recommended.

Depending on the skin condition, it may be done up to 4–5 sessions.

After the 3 sessions, maintenance treatments are performed every 3–6 months.

  1. How painful is it?

Rejuran HB contains lidocaine, so it tends to be less painful.

For Rejuran Healer, if anesthetic cream and nerve block anesthesia are used, the pain is not very uncomfortable.

Pain is often felt in the order of Healer > Eye > HB.

  1. Does swelling or bruising occur after the procedure?

Because Rejuran is not injected deeply, bruising does not occur much.

Small pinpoint marks may be visible, but they usually calm down in a day or two.

Areas with thin skin may show slight swelling.

  1. Can I go about daily life as usual?

After a day or two, makeup, going to work, and appointments are all possible.

Small pinpoint bleeding may be visible, but it does not greatly affect daily life.

Most people can return to daily life from the next day.

  1. Are there side effects or risks?

PN is an ingredient with a high level of safety.

All procedures can have allergies, but Rejuran has a very low incidence of allergic reactions.

It is a procedure with almost no special side effects.

It is a relatively safe procedure even for sensitive skin.

  1. Procedures that go well with Rejuran

The combination of Rejuran + Juvelook SB is the most effective.

When done together,

fine lines elasticity skin texture improvement effects

become better.

  1. Recommendations by skin type

Dry skin Acne-prone skin → HB

Fine lines Reduced elasticity → Healer

Fine lines around the eyes Dark circles → Eye

Choose according to your skin condition.

  1. How is the price determined?

Rejuran is determined by box unit.

Rejuran Healer → based on 2cc

Rejuran Eye / HB → based on 1cc

The price varies depending on the area, volume, and number of sessions.

Rejuran is a regenerative treatment that improves the skin itself in a healthier way.

If you have concerns about fine lines, reduced elasticity, or skin texture, it can be a good choice.

If you have any more questions, please leave them in the comments and I will explain in detail.

Thank you for reading this long post. This was Wi Yeong-jin.

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