When Do Rejuran I Effects Start? A Complete Guide to Skin Changes by Treatment Cycle

Fine lines under the eyes, dark circles, hollowness

We found the answer in salmon

Hello.

This is Beauty's Doctor, Wi Young-jin.

There are many people who are curious about Rejuran I, so I’ve put together a detailed explanation myself.

"How is it different from regular Rejuran?"

"Is it okay to inject it under the eyes?"

"When do the effects start to appear?"

I get these questions very often. Let me go through them one by one.

✅ What is Rejuran I?

Rejuran is a skin booster that directly injects polynucleotide (PN) extracted from salmon into the dermis layer of the skin.

The DNA components of salmon are very similar to the base composition of the human body, so they are known to cause very little foreign-body reaction and to have a high level of safety.

Creams or ampoules applied externally only work on the epidermis, the outermost layer of the skin,

but Rejuran is delivered directly into the dermis by injection, so it can stimulate the skin’s healing ability more deeply.

Rejuran I is the most premium product in the Rejuran lineup.

It has a thinner viscosity and is optimized for spreadability and absorption so that it can also be used on thin, sensitive areas such as around the eyes.

There are four formulations: Rejuran Healer, Rejuran HB, Rejuran I, and Rejuran S, so if your concern is the eye area, Rejuran I is the most suitable.

✅ How is it different from regular Rejuran?

There are several types of Rejuran.

Regular Rejuran Healer is used evenly across the entire face, and Rejuran I is a formulation specialized for the eye area.

The skin around the eyes is thin and is a highly mobile area, so if regular Rejuran is used as is, there can be stronger pain and more embossing.

Rejuran I is the product that solves this problem.

Compared with the other lines, the biggest difference is that it causes less pain, bruising, and embossing.

Also, thanks to its gentle viscosity optimized for the eye area, Rejuran I spreads naturally into the skin after injection and finishes without a lumpy feeling.

For people who wanted Rejuran around the eyes but were worried about pain or bruising, Rejuran I becomes a more realistic option.

✅ What effects can you expect?

You can expect improvement in fine lines under the eyes, reduction of dark circles, improved elasticity around the eyes, and skin regeneration effects.

Creams applied externally only work on the epidermis,

but Rejuran I delivers ingredients directly into the dermis, so it improves the skin’s internal environment itself.

It stimulates fibroblasts, encouraging the skin to produce collagen, elastin, and hyaluronic acid on its own.

Rather than filling something in, it helps your skin recover by itself, so the results are natural and long-lasting.

In particular, under-eye dark circles can have different causes—blood vessels, pigmentation, or hollowness—so the approach changes depending on the cause,

but Rejuran I improves the thickness of the skin itself through dermal regeneration, so it is especially effective for dark circles caused by hollowness and thinning.

The same goes for fine lines.

Rather than filling the surface, it works by increasing collagen within the skin, so wrinkles are smoothed out from the inside.

✅ When do the effects appear?

There is no immediate effect. I’m being honest about that.

Around 1 to 2 weeks after the procedure, you begin to feel the skin texture becoming smoother,

after about 2 weeks, as collagen regeneration becomes active, you can start to feel an improvement in elasticity.

Around 4 weeks later, as the density and thickness of the dermis increase, this is the stage when the skin barrier becomes firmer.

At this point, smaller pores and a brighter complexion also begin to stand out.

Under-eye results generally last for more than 1 year.

However, repeated treatments are needed for the effects to build properly.

Many people who say, "I only did it once and there was no effect" are often unaware of this.

This is a procedure that gets better over time.

Even if the changes seem minimal at first, after three or more sessions, you can feel a noticeably different eye area.

✅ How many sessions are needed?

It is standard to receive at least 3 sessions at 2- to 3-week intervals.

As the sessions accumulate beyond 3, the effects become deeper and last longer.

After that, it is good to continue with maintenance treatments once every 6 months to 1 year.

✅ Are there any precautions after the procedure?

You just need to follow a few simple guidelines.

Immediately after the procedure, embossing (raised injection marks) may appear, but this is a sign that the ingredients have been delivered well into the dermis.

In most cases, it disappears on the same day or within 1 to 2 days.

For 3 to 7 days after the procedure, please avoid alcohol, saunas, jjimjilbang, and strenuous exercise.

When your body temperature rises, it can irritate the treated area.

Flaking may occur, but this is part of the skin’s regeneration process, so it is best not to remove it forcibly.

Bruising or swelling may occur, but in most cases it naturally disappears within 1 week.

The under-eye area, where the skin is especially thin, may retain bruising a little longer.

For about 6 hours after the procedure, it is best to avoid direct irritation to the treated area.

✅ Who is it suitable for?

It is recommended for people with these concerns.

People bothered by fine lines under the eyes, people concerned about dark circles, people whose eye-area skin has become thinner and lost elasticity, and people who are told their under-eyes look sunken and make them look tired.

Rather than dramatic changes like lifting or fillers, it is the most suitable procedure for those who want a natural and healthy-looking eye area. Rejuran I is a premium skin regeneration procedure designed specifically for the eye area.

Rather than immediate changes, it is a procedure that improves gradually and naturally.

Consistent care, rather than a single treatment, creates the results, and the fact that those results last for more than 1 year is Rejuran I’s biggest strength.

Because under-eye concerns have many different causes, it is best to decide through consultation whether Rejuran I is right for you or whether it would be better to combine it with another procedure.

If you are currently worried about your eye area, this is a procedure worth seriously considering at least once.

If you have any questions, feel free to ask anytime in the comments! 😊

Thank you for reading this long post. This was Wi Young-jin.