Our skin reacts when it is exposed to external stimuli, and when foreign substances are introduced into the skin or a wound occurs, it carries out various cellular processes for repair. This is the kind of response the skin shows when it is stung or bitten by an insect, or when a wound occurs. You can think of this as a signal that the body is responding to foreign material or injury and that cells involved in recovery are gathering.

A dog stung by a bee
As an immediate response, the skin swells, turns red, and feels itchy or painful. At the center of this rapid bodily defense response, called inflammation, histamine secreted by various immune cells acts to produce the symptoms mentioned above.

The role of histamine is:
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It dilates nearby capillaries, increasing blood flow to the injured area.
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It dilates blood vessels and activates the endothelial cells that make up the inner lining of the blood vessels, promoting the binding of circulating white blood cells.
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By increasing capillary permeability and promoting the influx of plasma components as well as the supply of antimicrobial proteins and complement proteins to the injured area,
it causes the skin to become red and swollen and produces symptoms such as itching and stinging. This increased blood flow from vasodilation also increases the inflow of tissue fluid, causing the area to swell.

#Itchy eyes after double eyelid surgery also occur due to histamine and other substances secreted by these immune cells. In general, itching begins gradually around 3 to 4 days after surgery, becomes worse around the one-week mark, and then gradually subsides after that.

If the itching is very severe, you may rub and scratch the eye area. However, this behavior can cause a side effect in which the double eyelids become loosened, so rubbing your eyes after double eyelid surgery is not a good habit. #Antihistamines or #steroid ointment may help.

When the incision area becomes red two weeks after surgery, it is not a symptom caused by histamine secretion. For itching and stinging at this stage, #Triam injections are often more helpful than antihistamines.
